期刊简介

               本杂志是由中华人民共和国卫生主管,同济医科大学附属协和医院主办,国内外公开发行的学术性期刊,1996年被评为全国优秀期刊。辟有专家论坛、临床研究、实验研究、技术与方法、研究报告、综述、进修苑、学术争鸣、经验介绍及病例报告等多个栏目。                

首页>临床耳鼻咽喉头颈外科杂志
  • 杂志名称:临床耳鼻咽喉头颈外科杂志
  • 主管单位:中华人民共和国教育部
  • 主办单位:华中科技大学同济医学院附属协和医院
  • 国际刊号:1001-1781
  • 国内刊号:42-1764/R
  • 出版周期:半月刊
期刊荣誉:第二届国家期刊奖提名奖期刊收录:万方收录(中), 维普收录(中), 国家图书馆馆藏, 知网收录(中), 上海图书馆馆藏, CA 化学文摘(美), 文摘与引文数据库, 北大核心期刊(中国人文社会科学核心期刊), 统计源核心期刊(中国科技论文核心期刊), JST 日本科学技术振兴机构数据库(日)
临床耳鼻咽喉头颈外科杂志2018年第15期

MicroRNA作为甲状腺乳头状癌生物标记物的研究进展

胡仿玲;张思林;余杰情;周文胜

关键词:甲状腺乳头状癌, microRNA, 生物标记物, 诊断, 复发, 预后
摘要:Thyroid cancer is a common malignancy derived from the endocrine system and the incidence of thyroid cancer is on the rise.Papillary thyroid carcinoma (PTC) is the most common type, and 90% of PTC patients have long-term survival, but the recurrence rate is still as high as 30%.Current diagnostic and postoperative monitoring techniques have been developed, but their negative rates and interfering factors also occupy an absolute proportion, and lack specific markers for the prognosis of PTC.Studies have shown that microRNAs (miRNAs) are associated with the development, metastasis and invasiveness of PTC and as a biomarker to aid in the diagnosis and monitoring of recurrence, and to determine the prognosis for specific markers.The future of PTC diagnosis, treatment and improve prognosis has broad prospects.This review mainly describes the development of miRNA as biomarkers for the diagnosis, recurrence and prognosis of PTC.