期刊简介
本杂志是由中华人民共和国卫生主管，同济医科大学附属协和医院主办，国内外公开发行的学术性期刊，1996年被评为全国优秀期刊。辟有专家论坛、临床研究、实验研究、技术与方法、研究报告、综述、进修苑、学术争鸣、经验介绍及病例报告等多个栏目。
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首页>临床耳鼻咽喉头颈外科杂志
- 杂志名称：临床耳鼻咽喉头颈外科杂志
- 主管单位：中华人民共和国教育部
- 主办单位：华中科技大学同济医学院附属协和医院
- 国际刊号：1001-1781
- 国内刊号：42-1764/R
- 出版周期：半月刊
期刊荣誉：第二届国家期刊奖提名奖期刊收录：万方收录(中), 维普收录(中), 国家图书馆馆藏, 知网收录(中), 上海图书馆馆藏, CA 化学文摘(美), 文摘与引文数据库, 北大核心期刊(中国人文社会科学核心期刊), 统计源核心期刊(中国科技论文核心期刊), JST 日本科学技术振兴机构数据库(日)
OSAHS生物标己物的研究进展及意义
唐旋；杨立新；周宁；颜杰
关键词：睡眠呼吸暂停低通气综合征, 阻塞性, 生物标记物, 蛋白质组学, 代谢组学
摘要：To review the application of proteomics and metabolomics in the study of OSAHS biomarkers,and to open a new perspective for the study of OSAHS.At present,these studies are still in a very preliminary stage,the results are not always consistent,and far from the clinical application requirements.However,compared with traditional chemical methods,quantitative protein and metabolomics methods still have many advantages and have great clinical potential.Further studies of larger populations for more detailed grouping in the future are necessary to validate these results,and a more structured investigation in cell and animal models is necessary to determine their molecular mechanisms.In addition,the combination of different analytical platforms will be the ideal method for OSAHS biomarker research.In conclusion,the proteomics and metabolomics methods help us to better understand the potential mechanisms of OSAHS and to discover and develop personalized screening,diagnosis,prognostic and therapeutic strategies for future research.
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