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本杂志是由中华人民共和国卫生主管，同济医科大学附属协和医院主办，国内外公开发行的学术性期刊，1996年被评为全国优秀期刊。辟有专家论坛、临床研究、实验研究、技术与方法、研究报告、综述、进修苑、学术争鸣、经验介绍及病例报告等多个栏目。
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首页>临床耳鼻咽喉头颈外科杂志
- 杂志名称：临床耳鼻咽喉头颈外科杂志
- 主管单位：中华人民共和国教育部
- 主办单位：华中科技大学同济医学院附属协和医院
- 国际刊号：1001-1781
- 国内刊号：42-1764/R
- 出版周期：半月刊
期刊荣誉：第二届国家期刊奖提名奖期刊收录：万方收录(中), 维普收录(中), 国家图书馆馆藏, 知网收录(中), 上海图书馆馆藏, CA 化学文摘(美), 文摘与引文数据库, 北大核心期刊(中国人文社会科学核心期刊), 统计源核心期刊(中国科技论文核心期刊), JST 日本科学技术振兴机构数据库(日)
2型固有淋巴细胞和miR-155在变应性鼻炎中的研究现状
朱亚琼；刘月辉
关键词：鼻炎, 变应性, 2型固有淋巴细胞, miR-155
摘要：Allergic rhinitis (AR) is the Th2 inflammatory response that atopic individuals exposure to allergens,mediators released by IgE-mediated,and a variety of immunocompetent cells and cytokines involved.Group 2 innate lymphoid cells (ILC2) are a novel population of native lymphocyte,can secrete large amounts of Th2 cytokines to promote the development of allergic diseases after being activated.MiR-155 plays a vital role in the development of the immune system,the differentiation of immune cells,and the maintenance of immune function.Nasal mucosas from the patients with allergic rhinitis show enrichment for ILC2 and miR-155.Highly expressed miR-155 may enhance the level of IL-4 by promoting ILC2 expression,thereby promoting Th2 inflammatory response.This review focuses on the function and meaning of ILC2 and miR-155 in patients with Allergic rhinitis.
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